A 0-4 fiasco worried Real Madrid fans. In fact, many real Madrid celebrities are also quite helpless about this, such as Marcelo in Brazil. He knew that there was something wrong with Real Madrid’s line-up, and casemiro’s departure made the midfield empty, which was the most crucial reason for their loss to Manchester City. No, Marcelo immediately recommended a player to Real Madrid, his teammate Andrei in Nence, Froumy, who is a midfielder known as the new casemiro!

Casemiro once again became a hero after the barb broke the goal and helped Manchester United score the key 3 points 1-0. On the other hand, after losing casemiro, Real Madrid lost 4-0 to Manchester City and went out of the Champions League. Since casemiro left, Real Madrid’s midfield is particularly weak, which makes Marcelo in Brazil anxious. It can be seen how important an excellent midfielder is. It happens that Marcelo has such a player around him. He is the new Brazilian international-Andre!

Cammavinga left the most familiar middle road, and although he played well on the right, there was still a vacancy in Real Madrid’s midfield. Manchester City seized this gap, and it was difficult for modric and Cross to make up for the slow movement, so Real Madrid’s goal came naturally. This season’s crucial game, Real Madrid lost miserably, losing was small and losing face was big. After all, 0-4 was unexpected by most people. Reinforcement is imperative!

Hoarding the midfield is a precaution, because modric and Cross have a one-year contract at most. Today, Bellingham is infinitely close to Real Madrid, but they still want to buy more players, including multiple positions. Watching Ancelotti fall behind, you can see how weak Real Madrid’s bench is. Many people are worried about Real Madrid’s lineup in the new season, including Marcelo in Brazil.

According to Brazil’s Global Sports, Marcelo recommended his teammate Andre to Real Madrid in Nence, Froumy. Andre, 21, joined the Brazilian national team not long ago. He is a new generation of excellent midfielders emerging in Brazil. Don’t look at Andre’s "double 0" data with 0 goals and 0 assists this season, but Andre’s name has long been heard in Brazil, which shows his Excellence. At present, the value of players in Germany is only 14 million euros, which is very cost-effective.

Andre is regarded as a new generation of casemiro, and he has high hopes from fans. In a list of the most influential football players born in 2001 published by the football data structure CIES, Andre ranks sixth. Although far away from the European continent, Andre has a reputation, which shows that his strength is really good. It is worth noting that Fulham had offered 20 million euros earlier, but the player chose to stay in Nence, Froumy.

0 goals and 0 assists, Marcelo recommended to Real Madrid, which is enough to prove Andre’s Excellence. Secondly, Andre’s worth is not high, and Real Madrid can easily match his salary demand. Such a transaction will not affect the operation of Real Madrid. In the past, Real Madrid got many excellent players by digging for treasures, and Andre is also worth trying. Of course, Andre’s height is a big weakness. The height of 1.76 meters may suffer some losses in the fierce five leagues.

Inheriting the spirit of Lei Feng, scientific and technological volunteers are in action. In order to thoroughly implement the spirit of the General Secretary’s instructions, the Chinese Society of Artificial Intelligence actively responded to the call of the China Association for Science and Technology, and adhered to the principle that "research must take serving the country as its own responsibility, and learning must take serving the people as its glory". Through various forms of scientific and technological volunteer service activities, it profoundly interpreted the connotation of Lei Feng’s spiritual era and wrote the story of Lei Feng in the scientific and technological circles in the new era.

On March 5th, on the occasion of the 60th "Learning from Lei Feng", CAAI Smart Energy Committee organized and set up a volunteer service team for science and technology, entered the front line of science and technology companies, and carried out the activity of "Lecture on the Application of Artificial Intelligence in the Energy and Power Field under the Target of’ Double Carbon’".

This activity focused on the application scenarios of energy and electric power industry. The CAAI Smart Energy Committee invited experts in the fields of electric power and artificial intelligence to share popular science knowledge such as power grid dispatching, comprehensive energy, safety inspection and so on with front-line employees and the masses in the form of knowledge lectures. Actively interacted with the field personnel and invited them to experience the application of new power technologies such as VR. At the end of the activity, experts had in-depth exchanges with the audience and patiently answered questions of common concern such as the construction of new power systems.

Through this activity, the Science and Technology Volunteer Service Corps introduced the innovative applications of big data, artificial intelligence, virtual reality, metauniverse, ChatGPT and other technologies in the field of energy and power to the frontline employees and the masses who care about the development of the energy and power industry, and vigorously promoted the spirit of Lei Feng with practical actions and wrote the story of Lei Feng in the scientific and technological field in the new era.

On March 10, 2023, as of 10: 12, the intraday turnover of artificial intelligence ETF dropped slightly by 0.86%, reaching 26.82 million yuan, and the turnover continued to increase. The ETF closely tracks the CSI artificial intelligence theme index, which fell by 0.62%. In terms of related constituent stocks, Inspur Information fell by 3.98%, Desai Siwei fell by 3.31%, and Zhongke Chuangda fell by 2.89%; Yihualu rose by 19.75%, Mayer PaCO rose by 2.96%, and Dahua shares rose by 2.8%.

In the news, a few days ago, relevant departments said that emerging industries are the new pillars and new tracks that will lead the future development. It will focus on key areas such as 5G, artificial intelligence, bio-manufacturing, industrial Internet, intelligent networked vehicles, green and low carbon, and continuously enrich and expand new application scenarios. Expand the layout of the national manufacturing innovation center in emerging industries. Implement the "Robot+"application action to promote the large-scale and intensive development of the Internet of Things industry.

According to TF Securities’s analysis, the application of artificial intelligence covers computer vision, speech recognition, natural speech processing and data science. After deep learning was put forward in 2006, the AI industry entered a stage of rapid development. At present, it has been widely used in security, finance, medical care, smart cars and other fields to promote productivity progress. Artificial intelligence expenditure has become one of the main forces supporting the digital transformation expenditure of enterprises, and the market scale has grown rapidly. According to Sullivan’s report, the global expenditure on artificial intelligence technology will be 68.7 billion US dollars in 2020, and it is expected to reach 221.2 billion US dollars in 2025, with a compound annual growth rate of 26.3%, while China’s artificial intelligence market will reach 41.5%, which is expected to be the first in the world.

When I first learned about Feifan automobile, I was attracted by it. I must say, this car is really unbelievable.# New Deluxe Wisdom Block #

Let’s start with the design of the new luxurious wisdom seat. The exterior of this car looks very fashionable and high-end, equipped with many high-tech elements. What surprised me most was its interior design. The new luxury wisdom seat adopts artificial intelligence technology, which makes all kinds of operations in the car more intelligent. For example, the entertainment system in the car can not only play music and videos, but also connect with the mobile phone to track your health and schedule. In this way, you can handle all kinds of affairs while driving. In an increasingly fast-paced society, such a function will certainly attract many people’s attention.

In addition, the new luxury seat has a very cool feature, that is, the seat in the car can rotate freely. You can choose to sit facing forward or backward, or face left or right. This design is very suitable for social occasions or when you want to communicate with people in the car. This kind of design is something I have never seen before. It’s simply amazing.

Of course, as a high-end luxury car, the handling performance of the new luxury seat is also excellent. Its four-wheel drive system can help you drive safely in complex road conditions. In addition, the new luxury wisdom seat is also equipped with an advanced electric engine, which makes it equally outstanding in performance.

Generally speaking, Feifan’s new luxury seat is an excellent and forward-looking car for me. Its design embodies the application of artificial intelligence technology in the automobile industry, and the intelligent elements in the car are eye-catching. In addition, the new luxury wisdom seat is also excellent in performance. As Feifan Automobile advocates, "Let intelligence connect life", and the appearance of the new luxury wisdom seat may mark the beginning of an intelligent life based on artificial intelligence technology.

IFFHS (International Federation of Football History and Statistics) selected the list of the best coaches in the history of world football, and Mourinho won the first place in active service, scoring 242 points, beating Guardiola with 221 points. Together with the retired coach, Mu Shuai ranked second and Ferguson ranked first in history, with a score of 257. The top ten are Ferguson, Mourinho, Guardiola, Wenger, Loew, Ancelotti, Bosco, Simone, Lippi and Deschamps.

The selection mechanism is considered fair, and scores are counted according to the annual ranking of each category, including the annual ranking of national team coaches and the annual ranking of club coaches. The first place gets 20 points, the second place gets 19 points, the third place gets 18 points, and so on, the 20th place gets 1 point, and those below 20 places will not get points.

According to this list, Mu Shuai is undoubtedly the best coach in the world and has the highest score. What’s important is that Mourinho’s success has a high gold content, and it’s hard for anyone to repeat it. The key honor is to lead Porto, whose lineup is relatively mediocre, to win the Europa League and the Champions League in succession, to achieve the triple crown with Inter Milan, who is also not optimistic, to complete the triple crown in Manchester United’s trough, and to win the European championship in Rome.

Obviously, Mourinho is different from other coaches. He attaches great importance to the team’s fighting spirit and unity, is good at building a division of iron and blood, plays a super whole with a seemingly ordinary lineup, and supports his team to win five finals in Europe. Therefore, wherever Mourinho goes, there are a group of die-hard players, and even many people express the attitude of "a scholar dies for a confidant". The charm of personality is full, which has become a double-edged sword for Mu Shuai’s coaching. Some people who refuse to accept him will directly become thorns, and Bogba is one of them.

At present, in Rome, Mu Shuai has turned the team into a division of iron and blood, and has a strong performance in both Serie A and Europa League. In the 26th round of Serie A against Sassuolo, the winner will catch up with Inter Milan, which ranks second in the standings, and get 50 points. The European War is expected to recreate the myth of coaching Porto, leading the team to win the European Championship for two consecutive years, and it is at different levels. At present, one foot has entered the quarterfinals of the Europa League. However, Mu Shuai himself was in trouble. He scolded the fourth official in a 1-2 loss to Cremonese in round i24 of a shop and got a red card. After the game, he also received a ticket, suspended for two games and fined 10,000 euros. Mu Shuai chose the hard bar and directly sued the referee group because the fourth official provoked a scolding battle and then asked the referee to show the red card, implying that the referee intended to manipulate the game.

During the prosecution of the referee, Mu Shuai’s heavy penalty was not implemented. Mu Shuai led the team to win Juventus 1-0 and Real Sociedad 2-0 in the last two games. Now on March 11th, Jose Mourinho’s heavy penalty came into effect, and the Italian Football Association confirmed that Jose Mourinho failed to sue the referee. After the heavy penalty came into effect, Jose Mourinho issued a document to protest and directly made a handcuff gesture to express his strong dissatisfaction. This gesture appeared when he coached Inter Milan. Next, Mourinho will not be able to direct the two matches between Rome and Sassuolo in the 26th round of Serie A and Lazio in the 27th round, and the second leg of the Europa League quarter-final and Real Sociedad will not be affected by the league.

[Argentina players’ scoring list after the World Cup: lautaro scored 9 goals first, Di Maria scored 7 goals] SC_ESPN counted the scoring list of Argentina champions after the World Cup, and lautaro, Di Maria and Messi ranked in the top three.

Lautaro (Inter): 9 goals.

Di Maria (Juventus): 7 goals

Messi (Paris): 6 goals

Dibala (Rome): 5 goals

Mcallister (Brighton): 3 goals.

Julian Alvarez (Manchester City): 3 goals.

Angel Correa, acuna and Tiago almada: 2 goals.

The Italian Football Association officially announced that Rome’s appeal was rejected and that it would maintain Mourinho’s two-game ban and a fine of 10,000 euros.

In the match between Rome and Cremonese on February 28th, Mourinho was accused of making offensive remarks to the fourth official, and was subsequently sentenced to two games’ ban and a fine of 10,000 euros.

（Cinderella）

Edit | Chinese cabbage leaves

Antibiotic resistance is an increasingly serious health problem. Antimicrobial peptides (AMP) destroy harmful microorganisms through nonspecific mechanisms, making it difficult for microorganisms to develop drug resistance. Therefore, they are expected to be substitutes for traditional antibacterial drugs.

In this study, researchers from Gwangju Institute of Science and Technology (GIST) in Korea developed an improved AMP classification model called AMP-BERT.

The team proposed a deep learning model with a fine-tuned bidirectional encoder representation from Transformers(BERT) architecture, aiming at extracting structural/functional information from input peptides and identifying each input as AMP or non-AMP. The researchers compared the performance of this model with other models based on machine learning. AMP-BERT produced the best prediction results among all the models evaluated using external data sets selected by researchers.

In addition, researchers use the attention mechanism in BERT to perform interpretable feature analysis and identify specific residues in AMP that are known to contribute to peptide structure and antibacterial function. The results show that AMP-BERT can capture the structural characteristics of peptides used for model learning, so that AMP or non-AMP can be predicted from the input sequence. AMP-BERT is expected to help identify candidate AMPs for functional verification and drug development.

The study is based on "AMP-BERT: Prediction of antimicrobial peptide function based on a BERT modelThe title was published on December 3, 2022 in "Protein Science》。

In the past decades, antibiotic resistance has become a major public health problem in the world. This leads to the search for alternative methods to treat microbial infections.

One of the innovations is the discovery of antibacterial properties of some peptides. Antimicrobial peptide (AMP) is a short peptide found in most animals, plants and microorganisms, which can be used as a natural defense against infection. AMP fights against harmful bacteria through non-specific mechanism and prevents them from producing antibiotic resistance.

Despite these extraordinary abilities, the research on AMP is still hindered because the existing system for identifying candidate AMPs is like a black box, and the output is not easy to interpret for further analysis.

Now, in a breakthrough recently published by protein Science, a group of researchers from Gwangju Institute of Science and Technology, including Professor Hojung Nam and Mr Hansol Lee, put forward an AMP-BERT classification system, which uses AI-based bidirectional encoder representation from Transformers (BERT) architecture to improve the existing AMP classification model.

When asked about the motivation behind the development of the classification system, Professor Nam explained: "The abuse and overuse of antibiotics have led to the emergence of bacteria that cannot be effectively treated by these antibiotics. This not only increases human health risks, but also increases the health risks of agriculture. Therefore, we hope to develop an AMP pre-screening platform, which is not the black box of the algorithm, but can be easily explained for further research. 」

The team integrated a deep neural network based on natural language processing (NLP), which was pre-trained with billions of protein sequences and then fine-tuned with thousands of peptide sequences in the benchmark AMP database. This makes the AMP-BERT model not only extract structural and functional information from the input peptide sequence, but also distinguish AMP from non-AMP. This enhances the prediction ability and enables the model to make better classification even with external data.

The team also designed a model to assign a separate attention score to each amino acid in the input peptide sequence. Then, the attention characteristics reveal the important sub-regions of AMP, which play an important role in determining whether the peptide has antibacterial properties. In addition, the prediction results show that the applicability of AMP-BERT model even extends to invisible peptide data, and it can learn meaningful functional and structural information from these peptides.

The new AMP-BERT peptide pre-screening model can open a new door for discovering and developing AMP-based candidate drugs for the treatment of drug-resistant diseases. The important peptide subregion information provided by the prediction platform can also be used to optimize the antibiotic efficiency of peptides.

Professor Nam concluded: "As more and more AMPs are verified by experiments and new structural information is discovered by computational methods, we will be able to manufacture more effective antibiotic drugs and may prevent new pandemics from spreading around the world in the near future. 」

Data set:

Paper link:

Related reports:

Hong Kong Eastern are set to enjoy an extra day off before the Asean Basketball League (ABL) play-offs final tip off on Saturday.

But head coach Zeljko Pavlicevic played down the importance of any extra rest after the 2017 champions came from behind to defeat NS Matrix 76-70 at Nguyen Du Stadium in Ho Chi Minh City on Wednesday night, winning their semi-final series 2-0 against the Malaysian side.

In the other semi-final, Saigon Heat pushed the series to a decider with an 81-79 overtime win against Singapore Slingers, with Eastern’s opponents still yet to be confirmed.

“Yes, we will have one day off, then we will know who we will play and start making preparations like we always do,” veteran coach Pavlicevic said.

“These are experienced players who will be even more motivated under these kinds of situations. I do not want to say this is some kind of advantage.”

Facing a must-win game, NS Matrix – the only tournament debutants to reach the play-offs this season – came out more determined.